By A. H. , Tempest, D. W. , editors Rose
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Additional resources for Advances in Microbial Physiology, Vol. 15
In this niutant, the biochemical lesion was found to involve a loss of the low-affinity glucose transport system (see Section VII, C ; p. 5 3 ) . The causal relationship between this transport deficiency and the morphological growth rhythm has not been explored but its basis could reside in an altered plasma membrane. c . “MACROREGULATION” O F GROWTH A growth regulatory system recently has been described in Neurospora c r a m that may be an example of a distinct class of overall or macroregulatory” phenomena.
BULL AND A. P. J. TRlNCl continuous-flow cultures. Hardly any studies of this sort have been made of filamentous fungi but the value of the approach has been amply demonstrated by work with yeasts. When the Monod model is applied to the analysis of perturbations resulting from stepwise changes in, say, the dilution rate or growthlimiting substrate concentration, a smooth transition towards the new steady-state biomass concentration is predicted. However, much more complex transient state kinetics usually are encountered, and the results of work by Gilley and Bungay (1967) with Saccharomyces cerevisiae clearly illustrate this point.
It is possible that the peripheral growth zone of these hyphae is limited by the plugging of the septal pores (Trinci and Collinge, 1973). The plugging of septal pores may be initiated by the establishment in the medium of conditions which inhibit growth (see Section IV, B; p. 27). Septa1 plugging may thus be considered as an ageing phenomenon. As mentioned earlier, the establishment in the substrate of conditions which are unfavourable for growth is probably related to the rate of increase in biomass per unit area of substrate.
Advances in Microbial Physiology, Vol. 15 by A. H. , Tempest, D. W. , editors Rose